Dr. Eyal Zadicario is the COO of Insightec.

#73: Eyal Zadicario – Beyond the Scalpel: Towards an Acoustic Neurosurgical Suite with Insightec

In this episode of Stimulating Brains, we sit down with Dr. Eyal Zadicario, Chief Operating Officer at Insightec, to explore the remarkable evolution of focused ultrasound – from its experimental origins to its transformative role in functional neurosurgery today.

Dr. Zadicario shares insights from over two decades at the forefront of innovation, reflecting on the challenges of translating breakthroughs from academia to industry, designing clinician-friendly systems that prioritize the patient experience, and overcoming skepticism toward disruptive technologies.

Together, we revisit key milestones – from the first MRgFUS based thalamotomy in 2008 and early applications in breast cancer, to the expanding frontiers of neuromodulation. Looking ahead, we discuss the exciting possibilities of blood brain barrier opening, the acoustic neurosurgical suite, and even brain mapping through focused sound.

Tune in for a fascinating conversation on how precision acoustics are reshaping the landscape of brain therapy and beyond.

Taha, Alaa; Horn, Andreas (2025). #73: Eyal Zadicario – Beyond the Scalpel: Towards an Acoustic Neurosurgical Suite with Insightec. figshare. Media. https://doi.org/10.6084/m9.figshare.30573062

  • Post-treatment MRI following the first-ever transcranial thalamotomy performed in Zurich for neuropathic pain (2008).

  • The clinical team at Brigham and Women’s Hospital (BWH) during the first transcranial MR-guided focused ultrasound (MRgFUS) procedure (February 2005).

  • Essential tremor feasibility study conducted at the University of Virginia (UVA), marking a pivotal step in focused ultrasound therapy (February 2011).

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